The phospho-ester linkage is a chemical bond between a phosphate (acidic) and an alcohol in a process called esterification, where a water molecule is eliminated.
H3PO4 + ROH → H2PO4R + H2O
For example, the binding in ATP between alpha phosphate and ribose carbon 5 'is a phospho-ester bond. This type of bond (called low energy) differs from the phospho-anhydride (high-energy) bond between alpha / beta and beta / gamma phosphates in the ATP. Another example we find in the intermediate of 1,3-bisphosphoglycerate glycolysis (1-3-BPG) which contains two phosphoric bonds, but with different hydrolysis energy, a phospho-anhydride on carbon 1, and a phospho-ester on carbon 3 .
The hydrolysis energy is that energy that develops when a bond is broken and the functional meaning of the use of high energy molecules as a source of energy resides in the possibility of coupling a hydrolysis reaction of a high bond energy with a useful reaction that could not happen otherwise. In this way, the energy contained in "high energy molecules", such as ATP, is used. Voices correlateemodify wikitesto
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