Langendorff's isolated heart or heart is an in vitro technique used in pharmacology and physiology that allows to examine contractility and heart rate without the problems of in vivo methods.
His creator was Oskar Langendorff. Describe the wikitesto modification
The heart is quickly removed from the animal along with its vessels and is readily perfused retrograde with a hydrogen peroxide solution. Retrograde pressure allows the functioning of the aortic valve and the contractile button function of the heart drives the perfused through the coronary hosts, ensuring myocardial perfusion and consequently vitality of the organ for several hours.
Through perfused drugs can be infused so that their effect can be evaluated directly and without critical interference in in vivo experiments. Voices correlateemodify wikitesto
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