Derivatization


Derivatization means the process by which molecular functional groups are replaced by chemical reactions. Use in gas chromatography and wikitext modification

In gas chromatography, the functional groups that are to be replaced are: N-H, O-H and SH, so as to render volatile organic molecules more volatile.

This is to make it suitable for analysis in GC-MS molecules that otherwise would not.

Derivatization is divided into four groups, depending on the reaction used:

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